Seven Things You Should Know About Pain Science

In the previous post I discussed some common back pain myths, such as the ideas that bulging discs, “bad” posture, or lack of core strength are major causes of back pain. As I noted, the evidence just doesn’t support those claims, and this is somewhat surprising and counterintuitive. However, learning some basics of pain science will go a long way towards making this evidence more understandable.

Pain science has learned a great deal in the last fifty years, but most of this information has had seemingly little impact on the way pain is commonly treated. If you have pain, this is stuff you should know.  By the time you are done reading this post you will know more than many medical providers about pain mechanisms, and maybe even feel a little better as a result, because research shows that pain education can improve outcomes. Here are some basics ideas of pain science.

1.  Pain is a Survival Mechanism whose Purpose is to Protect the Body

Pain is defined as an unpleasant subjective experience whose purpose is to motivate you to do something, usually to protect body parts that the brain thinks (rightly or wrongly) are damaged. If you feel pain, it means that your central nervous system (“CNS”) thinks the body is under threat, and that something has to be done about it.  In this sense, pain is a survival mechanism of fundamental importance. People born without the ability to feel pain (yes, they really exist) don’t live very long. Your CNS takes its job of creating pain very seriously, and therefore you can expect that when it thinks a part of the body is being damaged, it will err on the side of giving you a clear incentive to do something about it.

2.  Pain is an Output of the Brain, Not an Input from the Body

This is the fundamental paradigm shift that has recently occurred in pain science. Pain is created by the brain, not passively perceived by the brain as a preformed sensation that arrives from the body. When a body part is damaged, nerve endings send a signal to the brain containing information about the nature of the damage. But no pain is felt until the brain interprets this information and decides that pain would be a good way to encourage you to take action that will help protect and heal the damage. The brain considers a huge amount of factors in making this decision and no two brains will decide the same thing. Many different parts of the brain help process the pain response, including areas that govern emotions, past memories, and future intentions. Therefore, pain is not an accurate measurement of the amount of tissue damage in an area, it is a signal encouraging action. When a professional musician hurts his hand, his brain might consider very different actions than a soccer player with the same injury. And therefore you can believe that he may get a very different pain response.

3.  Physical Harm Does not Equal Pain.  And Vice Versa.

If you are in pain, you are not necessarily hurt. And if you are hurt, you will not necessarily feel pain. A very dramatic example of tissue damage without pain occurs when a solider is wounded in battle, or a surfer gets an arm bitten off by a shark. In these situations, there is a good chance the victim will not feel any pain at all until the emergency is over. Pain is a survival mechanism, and in cases where pain makes survival even harder, we shouldn’t be surprised that there is no pain. Although most of us have never had our arms bitten off by sharks, we have likely experienced bumps or falls during a sports match or some other minor emergency that we didn’t feel until the game was over. Further, many studies have shown that large percentages of people with pain free backs, shoulders and knees have significant tissue damage in these areas that can be seen on MRI, such as herniated discs and torn rotator cuffs.

How can you have damage without pain? Because for some reason the brain doesn’t think that the damage calls for action. One possible explanation is that the damage occurred slowly over a long period of time in a way that the brain did not find threatening, or maybe the brain just figured the damage was healed as well as possible, and concluded that pain no longer served a useful function. If no action is useful or necessary, or if the action has already been taken, then there is no reason for pain. Have you ever gone to the doctor for pain that disappeared as soon as you walked into the doctor’s office? Perhaps this is the result of the brain relaxing after concluding that the action signal has been heard and that corrective action has been taken.

On the other hand, many people suffer from pain when there is no tissue damage at all. There is a horrible condition called allodynia, where even normal stimuli such as lightly touching the skin can cause excruciating pain. This is an extreme example of something that might occur quite commonly on a much smaller scale – the brain misinterprets innocuous sensory information as evidence of tissue damage, and causes unnecessary pain.

4.  The Brain Often “Thinks” the Body is in Danger Even When It Isn’t

The most dramatic example of this is phantom limb pain, when the victim feels pain in a missing body part. Although the painful limb has been gone for years and can no longer send signals to the brain, the part of the brain that senses the limb remains, and it can be mistakenly triggered by cross talk from nearby neural activity. When this occurs, victims might experience incredibly vivid and painful sensations of the missing limb. Amazingly, phantom arm pain can sometimes be cured by placing the remaining hand in a mirror box in a way that tricks the brain into thinking the missing arm is alive and well!  This is an extraordinary demonstration of the fact that the true target for pain relief is often the brain, not the body.

There are many other more commonplace instances where the brain does not know what is going on in the body and causes pain in an area that is clearly not under threat. Any kind of referred pain, where pain is felt a distance from the actual problem is an example of this. Allodynia is another example.

5.  Pain Breeds Pain

One unfortunate aspect of pain physiology is that the longer pain goes on, the easier it becomes to feel the pain. This is a consequence of a very basic neural process called long term potentiation, which basically means that the more times the brain uses a certain neural pathway, the easier it becomes to activate that pathway again. It’s like carving a groove through the snow while skiing down a mountain – the more times the same path is traveled the easier it is to fall into that same groove. This is the same process by which we learn habits or develop skills. In the context of pain, it means that the more times we feel a certain pain, the less stimulus is required to trigger the pain.

6.  Pain Can Be Triggered By Factors Unrelated to Physical Harm

You may have heard the phrase that neurons that fire together wire together.  The most famous example of this principle is Pavlov’s experiment where he rung a bell each time his dogs ate dinner, then later found that he could cause the dogs to salivate at the mere sound of the bell. What happened at the neural level is that the neurons for hearing the bell became wired to the neurons for salivating, because they fired together consistently for some time. The same thing can happen with pain. Let’s say that every time you go to work you engage in some stressful activity such as working on a computer or lifting boxes in a way that causes back pain. After a while your brain will start to relate the work environment to the pain, to the point where you can start feeling the pain just by showing up, or maybe even just thinking about work. It is no surprise that job dissatisfaction is a huge predictor of back pain.

Further, it has also been shown that emotional states such as anger, depression, and anxiety will reduce tolerance to pain. Although it is hard to believe, research provides strong evidence that a significant portion of chronic back pain is caused more by emotional and social factors than actual physical damage to tissues. You may have noticed that when you return to a place you haven’t been for many years, you quickly fall back into old patterns of speech, posture or behavior that you thought you had left behind permanently. Pain can be the same way, getting triggered or recalled by certain social contexts, feelings or thoughts that are associated with the pain. Ever notice that your pain went away went you went on vacation and came back when you returned?

7.  The CNS Can Change its Sensitivity Level to Pain

There are numerous mechanisms by which the CNS can increase or decrease its sensitivity to a stimulus from the body. The most extreme example of desensitization occurs during an emergency situation as described above, when pain signals from the body are completely inhibited from reaching the brain.

Most of the time an injury will increase the level of sensitization, presumably so that the brain can more easily protect an area that is now known to be damaged. When an area becomes sensitized, we can expect that pain will be felt sooner and more strongly, so that even normally innocuous mechanical pressures can cause pain. There are many complicated mechanisms by which the level of sensitivity is increased or decreased which are far beyond the scope of this article to address. For our purposes, the key point is that the CNS is constantly adjusting the level of volume on the pain signals depending on a variety of factors. For whatever reason, it appears that in many individuals with chronic pain, the volume has simply been turned up too loud and left on for too long.  This is called central sensitization, and it probably plays at least some role in many chronic pain states. It is another example of how chronic pain does not necessarily imply continuing or chronic harm to the body.

Conclusion

When the body is working well, damaged tissues will heal to the best extent possible in a few weeks or months, and then pain should end. Why should it continue if the body has already done its best to heal it?  When pain continues for long periods of time without any real source of continuing harm or damage, there might be a problem with the pain processing system, not the body. Put another way, if you have chronic pain, there is at least some chance that you are not really hurt. Research shows that for some people this is a comforting thought, and serves to reduce anxiety and stress and threat that makes pain worse.

So what else can we do with this info to help get out of pain? The bottom line is that we need to figure out what is causing the CNS to feel threatened and how can we reduce the threat. In the next post I’ll discuss some specific strategies based around movement.

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71 Responses to Seven Things You Should Know About Pain Science

  1. Erik Cisler says:

    Does absence of pain indicate absence of injury?

    I lost a fair bit of cartilage in my left knee over the years playing basketball. This was confirmed by constant pain and an MRI. I had microfracture surgery performed, but the surgeon figured it was a temporary stopgap procedure – my lesion was just too big to be fully corrected by simple microfracture. He told me I’d probably need an autologous chondrocyte implantation, which is an invasive procedure designed to embed new living cartilage in the affected area, or risk certain knee replacement surgery in a few years.

    I declined the surgery and have been exercising pain-free for about two years now. I squat, deadlift, sprint, hike, even play basketball, without any pain. I supplement with Vit D (or get lots of sun), Vitamin K2, and follow a paleo eating plan. No grains, sugar, seed oils – the basics. Obviously I’m not necessarily out of the woods yet, but I wonder if my lack of pain indicates some sort of recovery or a deadening of my pain receptors.

    Any thoughts?

    • Todd Hargrove says:

      Erik,

      Thanks for the comments, interesting story, you are a good example of what my post was about. Absence of pain does not indicate absence of tissue damage, but I do think it almost always indicates absence of problem to worry about. In my recent post I talked about the many ways that the pain alarm system can fail us by getting ramped up and start causing pain even without injury. I think is much less likely that the system will fail us by not alerting us to an injury that needs time to heal. I think the system is much more likely to err on the side of creating too much pain and not too little. So, if it doesn’t hurt, don’t worry about it! Of course be mindful that the knee might have a harder time taking extreme work than a younger one but if you just listen to your body I don’t think it will lie to you. Apparently your system is just like the many others that were measured in the above-referenced studies – an injury heals, objective damage remains, but function returns and pain is gone – exactly the way it’s supposed to work.

    • jack b says:

      Don’t confuse the paleo diet with how ancient peoples supposedly fed. No current paleo diet comes close to matching that. The most significant difference is that current paleo diets fail to incorporate the ingestion of feces from multiple sources: particularly other humans. Such additional “food” consumption likely accounts for heartiness in ancient peoples much more so than any other factor.

    • Kane says:

      I feel also their is a third element nerve signal — pain — level of suffering the third level.

  2. Erik Cisler says:

    One last thing, sorry:

    I also wonder if indeed significant structural damage remains, are the lack of pain and lack of immobility indications that the structural damage is no longer a problem?

    I guess I’m unclear whether structural/tissue damage is necessarily a bad thing. Pain may not exist now, and I may retain mobility and function, but will it manifest as something worse down the line?

    Interesting to think about. I suppose I’ll just have to wait and see, eh?

  3. […] Seven Things You Should Know About Pain Science « Better Movement […]

  4. Don’t know if “pain does not originate in the body, it originates in the brain” is a semantic shuffle or what. The signals of inflammation, damage, proprioception, etc. come from the CNS sending them up the spinal cord to the brain. I think how the brain processes that signal depends on where it’s processed in the brain. Lower-level functions are more ingrained and can’t be overridden much by the higher level functions. Eventually, the “bladder is full” message will win out no matter how much you try to hold it. The “my low back hurts when I do this” message can be ignored until the nervous system makes the signal louder because more damage is happening. Or the nerves arborize and grow larger to make a chronic neurogenic pain signal louder.

    Neurogenic “pain” is a pain signal generated by the nerves themselves and does not originate in the brain. You might want to investigate Don Hazen and Jon Martine’s classes on Nerve Mobilization. They may change your ideas about pain and it’s origins.

    • Todd Hargrove says:

      Michael,

      Your comment argues against an idea that does not appear in my blog, and in fact you have misquoted me. I never said that: “pain does not originate in the body, it originates in the brain.” Instead, I said that pain signals from the body do not result in pain until the brain interprets them and decides to create pain. This is a completely different idea. I’m not saying that pain cannot initiate in the body with nociception. Obviously it usually does, and this idea is specifically discussed in the post.

      I’m aware of Hazen’s and Martine’s work, but haven’t attended their classes. My guess is that they would not present a much different picture of nerve mechanics and pain science than that already described by Shacklock, Butler, Mosely, Brieg, Butler, Wall, Melzack, etc. If you would like to read several posts I wrote that are based on these authorities, you can search for the posts called Nerve Mechanics part I to III.

      • Jamie Brantley says:

        Michael,

        As a yoga teacher and biofeedback training provider in a small military communitity, I deal with a lot of clients, many who are soldiers, experiencing chronic pain, including LBP.

        I teach that pain is a signal from your body that something is “not right” and requires us to move or adjust in some way before lasting damage occurs. So I really appreciated your similar comments in this article.

        However, I find this discussion/argument about the statement “pain is created by the brain” is about semantics, as are most disagreements in the world. (I know I’m a little late to the party)

        In Eastern and natural health medicines and philosophies, pain is the “sensation (signal to the brain)” and suffering is the “human experience of pain (the brain’s interpretation of the signal).”

        This allows us to use pain as a guide for adjusting behaviors and actions to meet the body’s needs, and helps us to seperate suffering so we can make adjustments to deal with that as well. This also helps us to account for phantom and referred pain. In what I do, and how I help people, I find this distinction very useful.

        Thanks for the Article.

        • TOM says:

          It is not semantics at all. It is a real and important difference. The view you describe suggests that the brain has no option but to interpret certain sensory inputs as pain. The article argues otherwise, and is convincing.

    • Alexi winters says:

      I have terrible Chronic pain as I was dx with MS & Fibromyalgia 2003. Years before 1989 I underwent surgery & had a right Pyloplasty which was life threatening @ 18 yrs old. It was congenital & I had no idea that I had this until pain reared its ugly head.
      Now I have this terrible pain circulating daily & nothing helps, even Ketamin infusions to turn down the Ampage didn’t work. I am chemically sensitive to many medicines so I try & trust herbs to get me through the bad days.
      I totally agree that long standing old pain plays a massive role that Doctors don’t fully acknowledge the emotional response that this type of pain does to a person on a daily basis. I say out LOUD! THE ONLY WAY IS HERBAL & SPIRITUAL especially in these kind of case’s,when conventional medicine does not work. That said, even when pain is treatable with medicine spirituality is still key in the healing process.

      • Todd Hargrove says:

        Alexi,

        Sorry to hear about the pain. It must be an incredible challenge. Humans have the capacity to feel spiritual feelings, and I assume the evolutionary purpose of those feelings has something to do with making changes in what we consider to be meaningful. I am reminded that Lorimer Moseley has said that pain has a lot to do with assigning meaning to signals from the body. I have no doubt that accessing your spiritual side assists with your healing. Best of luck.

  5. Don Hazen says:

    Todd,

    With due respect, regarding your remark. “pain signals from the body do not result in pain until the brain interprets them and decides to create pain,” the statement is true but not very useful. The world doesn’t exist until the brain interprets it. But you don’t fix the paint job on your car by working on your brain, at least not generally.

    • Todd Hargrove says:

      Don,

      Thanks for commenting. I read some of your articles a while back and enjoyed them.

      You said: “With due respect, regarding your remark. “pain signals from the body do not result in pain until the brain interprets them and decides to create pain,” the statement is true but not very useful.”

      I’m not sure why you don’t find the statement useful. You have admitted it is true, and truth is generally useful, particularly when it corrects a misconception. Most people, and indeed most therapists, think that pain equals tissue damage, and this is undoubtedly false. Gaining a better understanding of the brain’s role in pain will lead many therapists or clients to reconsider their approaches to dealing with chronic pain. I will explain some strategies for targeting the brain in my next post.

      As to your analogy about the car, it would be a better analogy to chronic pain is we assume the possibility that the car’s paint job is fine, but only looks bad because the owner for some reason cannot see it clearly, perhaps because he is wearing sunglasses, or is colorblind, or is just depressed and cannot see anything but grey. If that was the case, you wouldn’t advise the person to keep repainting the car, you would try to get them to see the car more clearly. Similarly, when someone has chronic pain because of problem with the brain and not the body, I want to make the brain the target for my therapy, not the body.

    • regnalt says:

      Don,

      The body image and body schema are fundamental brain maps that are implicated in pain and can be worked on without focusing on the peripheral nerves. If the peripheral nerves are something to be addressed, which is possible, it is processed by the brain through instinctive, emotional, and/or volitional means – nerves can not be coerced by a practitioner if the brain doesn’t give the okay and this takes into account all of the circumstances involved — and it’s worth mentioning that nocioception isn’t a pain signal, per se, and that most people live with it all the time and don’t have pain!

      One more thought, the paint job analogy falls short, IMO, because human’s have a brain that allows for the mapping of space or in other words we CAN paint the proverbial car with our brains and if fact, the notion of ideomotor activity and feedforward processes do just that on a constant basis….

      Reg

  6. […] Seven things you should know about pain science […]

  7. […] the previous post I discussed the fact that chronic pain is sometimes not so much a problem with actual ongoing […]

  8. […] be the nervous system, which processes and controls pain.  Here are some posts on how that process works and what can be done with that information.  Thanks to Paul for pointing this out. Possibly […]

  9. […] basic strategies to reduce chronic pain, based on what we know about pain science.  As discussed here, chronic pain is sometimes not so much a problem with actual ongoing physical damage to the body, […]

  10. […] actual tissue damage to the body.  Put another way, errors in the way the brain maps the body can cause threat which causes pain, even when there is no damage at the site of […]

  11. Patrick says:

    Todd,

    Can a persons brain be in a mode of constant desensitization of pain?

    I never take any medications except for the rare occasion of a bad headache, I notice that when the pain reliever wears off, my whole body, at what I perceive to be inside of my bones, hurts for two days afterwards.

    Is it probable that my brain is naturally alleviating this pain through desensitization?

    Or do you think it is an adverse reaction to the pain reliever?

    If not could my brain be perceiving that something is wrong with my bones?

    I do not use any particular brand or type of pain reliever, just whatever is available at the time.

    • Todd Hargrove says:

      Patrick,

      I’m sorry to hear about that. I have never heard of such a problem, and I cant imagine why it would be happening. It sounds like you are having some sort of reaction to your pain relief medication. On the other hand, if you are getting the same reaction from different meds, then why? I would talk to a doc. Good luck.

  12. […] Pain is an evolutionary response that evolved to get you out of physical harm. Unfortunately, it doesn’t work all too well. […]

  13. Jana says:

    Good job Johanna! Seems like you’re in school again…. Very interesting read.

  14. Anoop says:

    Great job with the site, Todd!Love the article, love the website design too.

  15. […] readers of this blog know, I believe that many problems with chronic pain or physical performance are related to problems with the body maps. For example, as seen above, […]

  16. […] smudges, or or other inaccuracies in the body maps can be a significant contributing factor in many chronic pain conditions, and that fixing these problems is a potential way to cure […]

  17. […] more evidence that pain lives in the brain not the […]

  18. […] which compare the ideas of Dr. John Sarno to some new pain science concepts that I discussed here. While there may be some superficial similarities, there are some very important differences that I […]

  19. […] 2/20/11 WOD Rest CF Football Here CF Endurance Here Pain Lives in the Brain; Not the Body Everything You Need to Know, Right Here 5 Training Partners; 5 Lessons February 19th, 2011 | […]

  20. […] or have significant effects on various measures of health. Long term emotional stress is a killer. Pain is in the brain. So of course thoughts and feelings can affect the […]

  21. Mel John says:

    If my injury is as healed as it’s going to get then I don’t need the pain any more and any regime that will reduce or eliminate it is fine by me. At a very simple level I have found that engaging with the pain and actually saying out loud ‘Thank you for that information, there is no need to provide it again’ is surprisingly helpful.

  22. […] of the main themes of this blog is that therapies attempting to treat chronic pain should target the brain for change, not just the body. Some recent studies based around sensory […]

  23. […] the nervous system has concluded that stretching it is threatening to the safety of the body. The pain and stiffness are essentially protective mechanisms – ways to discourage you from lengthening it outside the perceived range of […]

  24. […] Seven Things You Should Know About Pain Science « Better MovementPain science has learned a great deal in the last fifty years, but most of this information has had seemingly little impact on the way pain is commonly treated.  If you have pain, this is stuff you should know.  By the time you are done reading this post you will know more than many medical providers about… […]

  25. Ali Nguyen says:

    One of the primary concerns I have, although I agree with everything you say, is that the body is not just a function of the brain. Although the brain has ultimate control over many aspects, it is ultimately stuck with the many conduits that lead to it, particularly the spinal cord and peripheral nerves. We can’t stop our reflexes as much as we can’t hold our breath for too long. In the case of chronic pain, where consistent peripheral nociceptor stimulation causes ongoing postural and reflexive behaviours, we become stuck, often in ‘maladaptive’ cycles that promotes further dysfunctional postural and reflexive behaviours. You can get the brain to ignore it for all you want, downregulate the inputs from the dysfunctional area, but the body will not ignore itself. One thing to note is that the brain interprets abnormal/excessive input from the periphery as harmful, not necessarily damage. It’s not only the brain, you have to also focus on the peripheries.

  26. […] don’t have any studies showing that unilateral interventions to address pain or coordination will have contralateral effects. However, I suspect that there are some relevant […]

  27. […] Seven Things you Should Know About Pain Science […]

  28. […] more articles on “Why Things Hurt”, check out these interesting articles: Seven Things You Should Know About Pain Science More on Pain and […]

  29. […] recommended on this blog (which is also one of the basic ideas in Z-Health): threat not only causes pain, it limits performance. If you want to increase performance, work to reduce […]

  30. […] Pain (and weakness) at a joint results from the brain’s opinion that the joint needs to be protected. There was something about my training session that convinced my brain that my knees were not as old as they thought they were, that they didn’t need as much protection as they were currently getting. So it gave me a longer leash to play with. This is why each training session should always send a little good news to the brain about the state of the body. […]

  31. […] Klokov 245 kg Rack Jerk   Seven Things You Should Know About Pain Science […]

  32. Reg Land says:

    Hello. I stumbled onto your web site by searching for the pain/mind connection on the web. Your information on pain is very curious to me for a number of reasons. As a result of a rather serious car wreck, the pain levels in my body are significant, even after a major surgery and even with pain meds taken on a daily basis. However, I have found that, with minor exception, during various right brain activities my pain levels decrease or vanish. When those activities cease, my pain returns. My primary activities are playing music (as a performer) and, more lately, dancing. So, I’m wondering if it is true that my pain is all in my head after all! I’m smiling as I write this but am taking seriously your writings about re-training one’s brain. It appears that, at least in my case, it is the left side of my brain that needs re-training. And I wonder if pain really resides just one side of the brain? Do you have any thoughts on or experience with this left/right side brain/pain connection?

    • Todd Hargrove says:

      Hi Reg,

      That is very interesting about the pain going away with music or dancing. I’m not sure what to make of that but it certainly is an interesting clue. Maybe its just good old fashioned distraction.

      One note – just because pain is “in the brain” doesn’t mean it is all “in your head.” It is a real thing, and it might be happening in large part because of actual damage in your body. Or not. Its hard to know!

      Best of luck with a full recovery.

    • Janelle says:

      I don’t know if it has as much to do with the activity being “right brain” as much as you are participating in meaningful, pleasurable activities, and as a result, your nervous feels “safe” and not requiring sending out those signals? I associate the same with deep, slow breathing an laughter.

  33. Andrew says:

    Hi Todd,

    Great post explaining some complex mechanisms in each to understand terms; do you mind if I use your post in clinic to assist with pain education of my patients?

    • Todd Hargrove says:

      Hi Andrew,

      Glad you like the post. And thanks for asking. Feel free to use it, with credit to the author.

  34. Jamie Brantley says:

    Todd,

    I would also like to use this post to educate clients (with credit to the author).

  35. Claire Hastie says:

    Is it true that the brain can only feel one pain at a time? Following a car crash I had acute/’sharp’ pain from a disk bulge in my neck causing brachialgia down my arm, and it was only in moments of relief from this ‘loud’ pain that I was aware of the chronic ‘dull’ pain in my lower back. I would be grateful to know whether you have evidence to support my experience, as my description of my experience is being used by an insurance company to undermine my claim for the operation I needed on my lower back. Please help! Thanks!

  36. Trevor says:

    Thanks for a great article Todd. I’ve learnt a huge amount reading your website and really appreciate the time you take to discuss the sometimes difficult to understand (at least for me) concepts of how pain really works. I’m find much of the information useful in building my understanding and helping me discuss with my massage clients why they may be experiencing pain and discomfort.
    Thanks again.

  37. jack b says:

    Article states “research shows that pain education can improve outcomes.” Is there a citation(s) you can direct me to? I suffer with severe chronic back and neck pain and have so for the past 11 years. After countless hours of research on pain over that time, I find the topic to be utterly depressing. There are undoubtedly some victories (solutions) for some people’s pain, but for those of us who have tried every evidenced-based treatment without success, the true state of medical knowledge in treating pain is clearly still infantile. And from everything I read, that is likely to be the case into the foreseeable future. Still holding out hope though that a new painkiller might make it to market. Other than that, it appears I’m destined to fall (painfully) through the cracks.

  38. Toria says:

    What a marvellously well written article! This explains chronic pain so clearly and comprehensively.

    • Billy Sweeney says:

      I haven’t read the article yet. As a 14 year sufferer of CHRONIC PAIN I was just too excited to leave a post about how my body found a way to stop a very bad type of pain. 14 years. So I see your post and I’m thinking it’s a joke because i have heard it all, or have I ? I will be back after i read…

    • Billy says:

      Wow. I am humbled. At 47 I am Jaded. 4 spine operations have left me with almost constant chronic pain, I usually piss my pants after long car rides and i ALWAYS piss my pants either on or after vacation for long periods of time. the more activity, the more pain. I bet your real happy to hear about me pissing my pants?? I do have a great pain doctor. I can go back on Narcotics but if i do…. Yep, it will be for life… There is so much more I have learned on my own. There is a drug from South America that you can take and it rebuilds the brains neuro transmitters that get killed or become inactive after long term use or even abuse of narcotic pain meds. ABUSE? Another reason I don’t like the pain med route. Say I don’t abuse which I won’t. Yet i will proceed onward into a “controlled” medical addiction. seriously, they will up my dose as I become more and more tolerable. As high as 240mg of Oxycontin a day followed by a muscle relaxer, and Xanax or Valium. I refer to them as the three kings. All stuff i learned by being in pain. You can start out on 2 kings, the muscle relaxer & the Valium or Xanax but most Docs should start you out with a much lower dose narcotic like Vicodin or whatever they call it now… Actually a good doctor should send you right to a pain specialist or become one himself. The BEST PART? The real best part???? The fucking pill popping fuckers that fake their pain or heroin addicts that steal anything!!! Yeah, i get grouped in with them if i choose the med route… POT! Yes if helps a ton with pain and may have even helped with this new thing I am experiencing. BUT when the DEMON PAIN comes knocking?? he ain’t looking to do bong hits…. That’s me… Now i have a blood clot to go along with my painful swollen leg. Also, I have a whole new blood disorder to compliment everything. Not bad, half the population has it and only about 1% know it. That’s not a bad thing because if we extrapolate that 1% out to another 100% only 1% of those would have any problems to go along with this genetic blood disorder…. Guess who the lucky guy is?? I am playing the lottery tonight be cause i just hit the world lottery of probable illnesses… I think the disorder is MTHR FR. Nope, not kidding…

      • Billy says:

        I almost forgot, This was a well written article. PLEASE give a copy to my doctors… How can you have damage without pain? Because for some reason the brain doesn’t think that the damage calls for action. One possible explanation is that the damage occurred slowly over a long period of time in a way that the brain did not find threatening, or maybe the brain just figured the damage was healed as well as possible, and concluded that pain no longer served a useful function. If no action is useful or necessary, or if the action has already been taken, then there is no reason for pain. Have you ever gone to the doctor for pain that disappeared as soon as you walked into the doctor’s office? Perhaps this is the result of the brain relaxing after concluding that the action signal has been heard and that corrective action has been taken.

  39. Billy Sweeney says:

    Wow! Sorry, i didn’t even read this article yet but i have to know something…….
    I have suffered with back pain for over 14 years. It is chronic but the pain levels do fluctuate. Yes, seasonal and weather are big players in that department. I have also come to KNOW the unless a doctor has felt REAL BAD PAIN he will not know you like others who suffer. There is a bunch of something…. But hey, I’m old, oder, and I’m beginning to hate everything. See, I’m a little normal. Anyway, winter wreaks havoc on my spine. I get a 24/7 sciatic pain accompanied by leg cramps that come calling at night. The BRIGHT SPOT! Oh, my meds. A very rare Valium and marijuana. I once consumed vast amounts of narcotic SLAVE DRUGS. I digress. the bright spot! When I have this chronic lasting pain I have discovered that my mind, brain, body, maybe evenself have built some sort of force field against outward sources that cause implosive onset pain. Anything from sneezing, to stepping off of the curb wrong and back to adjusting yourself in your chair. When one is experiencing 24/7 pain these little instances can cause loud screams to ER visits. At a strong 14 years into a life of pain I have just started to notice that when these pains should be hitting they feel more like painless jolts. It is really more like a compression explosion felt crossing the outside of the skull. It warms the brain and once yo understand what just happened you even get a lil jolt of euphoria. Being that marijuana is my main source of pain medication i would love to give it the props, and it does deserve props but i am more inclined to believe my body and brain evolved to where it can predict and prevent. Years upon years of the big guy pat on the back???/ Don’t get me started!! Today that would feel like an Irish Beat Down. Being IRISH I became a quick expert at avoiding my excited friends when they want to give me that haven’t seen ya in so long type of love. You know us Irish. There i go again.. so I have built some sort of force-field, or so i believe. has anyone had similar experiences???

  40. Herbert Silver says:

    I completely understand where pain sciences are going but I take issue with this statement “When the body is working well, damaged tissues will heal to the best extent possible in a few weeks or months, and then pain should end.” The assumption is that there was an injury and the problem resolves itself. This “pure” process doesn’t necessarily occur even with an ankle sprain. It doesn’t necessarily occur with a torn labrum. For a long time, MRI imaging wasn’t sensitive enough to detect a labral tear in the shoulder but it was certainly “there.” And, while I certainly don’t advocate a bunch of surgery, repairing the tear, even after years, may allow that lesion to finally heal. Someone with knee pain and significant degenerative changes may have (and sometimes may not have) severe pain in that knee. Is the pain “in the brain?” If that is the case, why do people feel so much better after knee replacements? In many of your posts, you point out that movement should be natural but at some point, for example, after injury, it might become complex. My own observations (and I admit these are observations, anecdotal)as far as treating chronic back pain is that there are lesions that are noted on physical examinations that are not noted on radiological studies. Once someone has hurt for many weeks, or months and certainly if they have hurt for years, it is not difficult to understand that their pain has been potentiated by the CNS. But, it is a grave misservice to say that just because a lesion is difficult to detect and might require skills that take at least months if not years to acquire that there isn’t some lesion that is contributing to someone’s chronic pain. Telling someone that their pain is ALL in their brain is just a cop out for poor diagnostic skills on the part of the clinician. Certainly, injuries should heal in a few weeks. But we have many examples of lesions that don’t heal and can be surgically corrected and then heal. Even a wound doesn’t always heal. And, like I said, even with the most advanced diagnostic imaging, these lesions are not self evident. Some “lesions” are movement dysfunctions that contribute to abnormal muscle function (over use, under use) with pain that persists. Telling someone to move correctly doesn’t remove that lesion. Telling someone that the reason that they have pain in their gluteal muscles is because their “pain is in their brain” while ignoring that they have abnormal movement patterns that an explain their pain is a remarkably large leap in what science is saying. The “brain pain” science can help explain why someone can not be hurting and with the most innocuous movement, or with lack of sleep or slightly increased stress all of a sudden hurts incredibly with nothing in between–just 0-60 without and 10, 20 or 30! That is the benefit of pain sciences because “normal” pain doesn’t do that. But I would say that in many cases there are underlying lesions that clinicians are just poor at diagnosing.

  41. Ravi says:

    If not brain, CNS, who is the ‘we’ feeling the pain?

  42. Joseph O says:

    Very good article. I’ve been a chronic pain sufferer longer than I’ve known. (I know that sounds backwards). The pain eventually caused constant aches and pain and generally foul mood. But any attempts at “psychiatric” intervention only made me more unstable. While most people would curse the day that they “threw their back out” or whatever and had to get the X-Rays, and MRI’s, it got me on a road to recovery. Now (at 46) I have 8 herniated discs, 4 in my lumbar spine, 4 in my neck, and a rather painful (but the docs say it shouldn’t hurt), 6 year old compression fracture in my thoracic spine, which is “healed/arthritic” at this point.

    My question is related to treatments to neuropathic pain. I’ve taken various medicines used to treat it, and it works for a while, but often, (especially with the anti-eplileptics) I end up getting in a foul mood after a few weeks treatment. After stopping it, I end up in excruciating pain while my brain re-adjusts it’s neurotransmitters and re-desensitizes the area. Does that sound about right? I just want to make sure I understand the concepts before trying a different medication, also, I’ll have my PM prescribe it as opposed to my psychiatrist, I just don’t think he is able to keep up enough with current medicine, except for what big pharma reps tell him.

    Thanks,

    Joe

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